Premium
Electrochemical Radical Silyl‐Oxygenation of Activated Alkenes
Author(s) -
Ke Jie,
Liu Wentan,
Zhu Xujiang,
Tan Xingfa,
He Chuan
Publication year - 2021
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.202016620
Subject(s) - silylation , organosilicon , silanes , electrochemistry , chemistry , radical , catalysis , cyanohydrin , substrate (aquarium) , photochemistry , organic chemistry , combinatorial chemistry , electrode , oceanography , silane , geology
An efficient electrochemical radical silyl‐oxygenation of electron‐deficient alkenes is demonstrated, which gives access to a variety of new highly functionalized silicon‐containing molecules, including β‐silyl‐cyanohydrin derivatives in good yields with excellent chemo‐ and regio‐selectivity. This electrochemical radical silylation process conducts under mild conditions without the use of transition metal catalyst or chemical oxidant and exhibits a wide scope of substrate silanes with high functional‐group tolerance. The ability to access silyl radicals using electrochemical Si−H activation offers new perspectives for the synthesis of valuable organosilicon compounds in a sustainable and green manner.