Hybrid Wireframe DNA Nanostructures with Scaffolded and Scaffold‐Free Modules | Zendy

Cui Yan | Zendy; Yan Jun | Zendy; Wei Bryan | Zendy

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Hybrid Wireframe DNA Nanostructures with Scaffolded and Scaffold‐Free Modules

Author(s) -

Cui Yan,

Yan Jun,

Wei Bryan

Publication year - 2021

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.202015564

Subject(s) - dna origami , scaffold , nanotechnology , dna nanotechnology , nanostructure , computer science , simple (philosophy) , dna , materials science , chemistry , biochemistry , philosophy , epistemology , database

The scaffolded DNA origami approach and the scaffold‐free LEGO approach both demonstrate an extraordinary self‐assembly capability for constructing all kinds of complex DNA nanostructures. Combining the construction elements of the two approaches, we introduce a hybrid framework to build wireframe structures in this study. A collection of two‐dimensional (2D) and three‐dimensional (3D) wireframe structures are presented to showcase the simple and versatile design. Our development reveals more of the ever‐expanding design space of structural DNA nanotechnology.

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