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Hybrid Wireframe DNA Nanostructures with Scaffolded and Scaffold‐Free Modules
Author(s) -
Cui Yan,
Yan Jun,
Wei Bryan
Publication year - 2021
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.202015564
Subject(s) - dna origami , scaffold , nanotechnology , dna nanotechnology , nanostructure , computer science , simple (philosophy) , dna , materials science , chemistry , biochemistry , philosophy , epistemology , database
The scaffolded DNA origami approach and the scaffold‐free LEGO approach both demonstrate an extraordinary self‐assembly capability for constructing all kinds of complex DNA nanostructures. Combining the construction elements of the two approaches, we introduce a hybrid framework to build wireframe structures in this study. A collection of two‐dimensional (2D) and three‐dimensional (3D) wireframe structures are presented to showcase the simple and versatile design. Our development reveals more of the ever‐expanding design space of structural DNA nanotechnology.