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Back Cover: Single‐Molecule 3D Orientation Imaging Reveals Nanoscale Compositional Heterogeneity in Lipid Membranes (Angew. Chem. Int. Ed. 40/2020)
Author(s) -
Lu Jin,
Mazidi Hesam,
Ding Tianben,
Zhang Oumeng,
Lew Matthew D.
Publication year - 2020
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.202011444
Subject(s) - membrane , nanoscopic scale , orientation (vector space) , lipid bilayer , molecule , cover (algebra) , chemistry , materials science , biophysics , nanotechnology , biochemistry , organic chemistry , biology , mechanical engineering , geometry , mathematics , engineering
The rotational dynamics of single fluorescent dyes are influenced by their surrounding nano‐environment within lipid membranes. In their Research Article on page 17572, M. D. Lew and co‐workers show that super‐resolved imaging of molecular orientation and wobble in 3D resolves lipid composition, liquid‐ordered and ‐disordered phases, and enzyme activity in membranes.