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Photocatalytic Fluoro Sulfoximidations of Styrenes
Author(s) -
Wang Chenyang,
Tu Yongliang,
Ma Ding,
Bolm Carsten
Publication year - 2020
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.202005844
Subject(s) - hypervalent molecule , regioselectivity , reagent , chemistry , fluorine , substrate (aquarium) , organic chemistry , photocatalysis , combinatorial chemistry , photochemistry , catalysis , oceanography , geology
Reactions of difluoroiodotoluene with NH‐sulfoximines provide new hypervalent iodine(III) reagents, which photocatalytically transfer a fluoro and a sulfoximidoyl group onto styrenes with high regioselectivity. The substrate scope is broad with respect to both sulfoximines and olefins. Following an operationally simple protocol, a large library of fluorine‐containing N‐functionalized sulfoximines can be accessed. Results from mechanistic investigations revealed the importance of radical intermediates.