Enantioselective S−H Insertion Reactions of α‐Carbonyl Sulfoxonium Ylides | Zendy

Momo Patrícia B. | Zendy; Leveille Alexandria N. | Zendy; Farrar Elliot H. E. | Zendy; Grayson Matthew N. | Zendy; Mattson Anita E. | Zendy; Burtoloso Antonio C. B. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Enantioselective S−H Insertion Reactions of α‐Carbonyl Sulfoxonium Ylides

Author(s) -

Momo Patrícia B.,

Leveille Alexandria N.,

Farrar Elliot H. E.,

Grayson Matthew N.,

Mattson Anita E.,

Burtoloso Antonio C. B.

Publication year - 2020

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.202005563

Subject(s) - enantioselective synthesis , thiourea , aryl , chemistry , catalysis , insertion reaction , combinatorial chemistry , medicinal chemistry , organic chemistry , alkyl

The first example of enantioselective S−H insertion reactions of sulfoxonium ylides is reported. Under the influence of thiourea catalysis, excellent levels of enantiocontrol (up to 95 % ee ) and yields (up to 97 %) are achieved for 31 examples in S−H insertion reactions of aryl thiols and α‐carbonyl sulfoxonium ylides.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research