Intramolecular Benzyne–Phenolate [4+2] Cycloadditions | Zendy

Takikawa Hiroshi | Zendy; Nishii Arata | Zendy; Takiguchi Hiromu | Zendy; Yagishita Hirotoshi | Zendy; Tanaka Masato | Zendy; Hirano Keiichi | Zendy; Uchiyama Masanobu | Zendy; Ohmori Ken | Zendy; Suzuki Keisuke | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Intramolecular Benzyne–Phenolate [4+2] Cycloadditions

Author(s) -

Takikawa Hiroshi,

Nishii Arata,

Takiguchi Hiromu,

Yagishita Hirotoshi,

Tanaka Masato,

Hirano Keiichi,

Uchiyama Masanobu,

Ohmori Ken,

Suzuki Keisuke

Publication year - 2020

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.202003131

Subject(s) - aryne , intramolecular force , cycloaddition , vicinal , chemistry , halogen , medicinal chemistry , stereochemistry , organic chemistry , catalysis , alkyl

An intramolecular benzyne–phenolate [4+2] cycloaddition is reported. Benzyne precursors, having vicinal halogen‐sulfonate functionalities, linked with a phenol(ate) by various tether groups undergo efficient intramolecular [4+2] cycloaddition by treatment with either Ph 3 MgLi or n BuLi for halogen–metal exchange to form various benzobarrelenes.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research