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Oxidative Addition of Alkenyl and Alkynyl Iodides to a Au I Complex
Author(s) -
Cadge Jamie A.,
Sparkes Hazel A.,
Bower John F.,
Russell Christopher A.
Publication year - 2020
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.202000473
Subject(s) - oxidative addition , chemistry , bimetallic strip , stoichiometry , oxidative phosphorylation , iodide , intermolecular force , medicinal chemistry , photochemistry , catalysis , organic chemistry , molecule , biochemistry
The first isolated examples of intermolecular oxidative addition of alkenyl and alkynyl iodides to Au I are reported. Using a 5,5′‐difluoro‐2,2′‐bipyridyl ligated complex, oxidative addition of geometrically defined alkenyl iodides occurs readily, reversibly and stereospecifically to give alkenyl‐Au III complexes. Conversely, reversible alkynyl iodide oxidative addition generates bimetallic complexes containing both Au III and Au I centers. Stoichiometric studies show that both new initiation modes can form the basis for the development of C−C bond forming cross‐couplings.