Premium
Frontispiece: Visualizing Microglia with a Fluorescence Turn‐On Ugt1a7c Substrate
Author(s) -
Kim Beomsue,
Fukuda Masahiro,
Lee JungYeol,
Su Dongdong,
Sanu Srikanta,
Silvin Aymeric,
Khoo Audrey T. T.,
Kwon Taejoon,
Liu Xiao,
Chi Weijie,
Liu Xiaogang,
Choi Sejong,
Wan Diana S. Y.,
Park SungJin,
Kim JinSoo,
Ginhoux Florent,
Je H. Shawn,
Chang YoungTae
Publication year - 2019
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201982461
Subject(s) - microglia , fluorescence , substrate (aquarium) , chemistry , fluorophore , turn (biochemistry) , biophysics , photochemistry , biochemistry , biology , optics , physics , ecology , immunology , inflammation
Fluorescent Probes In their Communication on page 7972 ff., H. S. Je, Y.‐T. Chang, and co‐workers describe the imaging of live microglia using the probe CDr20. Ugt1a7c catalyzes the glucuronidation of CDr20, resulting in red fluorescence.