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Inside Cover: Radical Acylfluoroalkylation of Olefins through N‐Heterocyclic Carbene Organocatalysis (Angew. Chem. Int. Ed. 5/2020)
Author(s) -
Li JunLong,
Liu YanQing,
Zou WenLin,
Zeng Rong,
Zhang Xiang,
Liu Yue,
Han Bo,
He Yu,
Leng HaiJun,
Li QingZhu
Publication year - 2020
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201915594
Subject(s) - carbene , organocatalysis , chemistry , cover (algebra) , organic chemistry , catalysis , enantioselective synthesis , mechanical engineering , engineering
The multicomponent acylfluoroalkylation of olefins through N‐heterocyclic carbene (NHC) organocatalysis is presented by J.‐L. Li, B. Han, Q.‐Z. Li and co‐workers in their Research Article page 1863. A broad spectrum of olefins, including styrenes, cyclic alkenes, indoles, vinyl ethers, vinyl esters, and unactivated alkenes, are compatible with this system. The generality of this method is further highlighted by the late‐stage modification of pharmaceutical skeletons.