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Inside Cover: Palladium–Borane Cooperation: Evidence for an Anionic Pathway and Its Application to Catalytic Hydro‐/Deutero‐dechlorination (Angew. Chem. Int. Ed. 52/2019)
Author(s) -
Kameo Hajime,
Yamamoto Jun,
Asada Ayaka,
Nakazawa Hiroshi,
Matsuzaka Hiroyuki,
Bourissou Didier
Publication year - 2019
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201914554
Subject(s) - borane , palladium , chemistry , catalysis , halogenation , hydride , ammonia borane , aryl , migratory insertion , medicinal chemistry , reductive elimination , lewis acids and bases , combinatorial chemistry , metal , polymer chemistry , photochemistry , organic chemistry , alkyl , hydrogen production
Metal–Lewis‐acid cooperation enables a new anionic pathway for palladium catalysis, as reported by H. Kameo, D. Bourissou et al. in their Communication on page 18783. The electron‐enriched Pd 0 , generated from hydride insertion into a Pd→B bond, activates chloroarenes, affording dehalogenation products via a B‐to‐Pd hydride transfer and reductive elimination. This new type of palladium–borane cooperation results in an efficient catalytic activity for hydro‐ and deutero‐dehalogenation of (hetero)aryl chlorides.