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Homochiral MOF–Polymer Mixed Matrix Membranes for Efficient Separation of Chiral Molecules
Author(s) -
Lu Yizhihao,
Zhang Huacheng,
Chan Jun Yong,
Ou Ranwen,
Zhu Haijin,
Forsyth Maria,
Marijanovic Emilia M.,
Doherty Cara M.,
Marriott Philip J.,
Holl Mark M. Banaszak,
Wang Huanting
Publication year - 2019
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201910408
Subject(s) - membrane , molecule , polymer , materials science , chemical engineering , matrix (chemical analysis) , polymer chemistry , chemistry , organic chemistry , composite material , biochemistry , engineering
Homochiral metal–organic framework (MOF) membranes have been recently reported for chiral separations. However, only a few high‐quality homochiral polycrystalline MOF membranes have been fabricated due to the difficulty in crystallization of a chiral MOF layer without defects on porous substrates. Alternatively, mixed matrix membranes (MMMs), which combine potential advantages of MOFs and polymers, have been widely demonstrated for gas separation and water purification. Here we report novel homochiral MOF–polymer MMMs for efficient chiral separation. Homochirality was successfully incorporated into achiral MIL‐53‐NH 2 nanocrystals by post‐synthetic modification with amino acids, such as l ‐histidine ( l ‐His) and l ‐glutamic acid ( l ‐Glu). The MIL‐53‐NH‐ l ‐His and MIL‐53‐NH‐ l ‐Glu nanocrystals were then embedded into polyethersulfone (PES) matrix to form homochiral MMMs, which exhibited excellent enantioselectivity for racemic 1‐phenylethanol with the highest enantiomeric excess value up to 100 %. This work, as an example, demonstrates the feasibility of fabricating diverse large‐scale homochiral MOF‐based MMMs for chiral separation.