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Regioselective Oxidative Arylation of Fluorophenols
Author(s) -
Yu Congjun,
Patureau Frederic W.
Publication year - 2019
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201910352
Subject(s) - regioselectivity , oxidative phosphorylation , chemistry , generality , combinatorial chemistry , organic chemistry , catalysis , biochemistry , psychology , psychotherapist
A metal free and highly regioselective oxidative arylation reaction of fluorophenols is described. The relative position of the fluoride leaving group (i.e., ortho or para ) controls the 1,2 or 1,4 nature of the arylated quinone product, lending versatility and generality to this oxidative, defluorinative, arylation concept.