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Arene‐Free Ruthenium(II/IV)‐Catalyzed Bifurcated Arylation for Oxidative C−H/C−H Functionalizations
Author(s) -
Rogge Torben,
Ackermann Lutz
Publication year - 2019
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201909457
Subject(s) - ruthenium , reactivity (psychology) , catalysis , chemistry , selectivity , ligand (biochemistry) , combinatorial chemistry , oxidative phosphorylation , stereochemistry , medicinal chemistry , organic chemistry , receptor , biochemistry , medicine , alternative medicine , pathology
Experimental and computational studies provide detailed insight into the selectivity‐ and reactivity‐controlling factors in bifurcated ruthenium‐catalyzed direct C−H arylations and dehydrogenative C−H/C−H functionalizations. Thorough investigations revealed the importance of arene‐ligand‐free complexes for the formation of biscyclometalated intermediates within a ruthenium(II/IV/II) mechanistic manifold.