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Regio‐ and Stereoselective Synthesis of Fully Substituted Silyl Enol Ethers of Ketones and Aldehydes in Acyclic Systems
Author(s) -
Wang PeterYong,
Duret Guillaume,
Marek Ilan
Publication year - 2019
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201909089
Subject(s) - stereoselectivity , silylation , enol , chemistry , organic chemistry , catalysis
The regio‐ and stereoselective preparation of fully substituted and stereodefined silyl enol ethers of ketones and aldehydes through an allyl‐Brook rearrangement is reported. This fast and efficient method proceeds from a mixture of E and Z isomers of easily accessible starting materials.