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DNA Origami Nanoplate‐Based Emulsion with Nanopore Function
Author(s) -
Ishikawa Daisuke,
Suzuki Yuki,
Kurokawa Chikako,
Ohara Masayuki,
Tsuchiya Misato,
Morita Masamune,
Yanagisawa Miho,
Endo Masayuki,
Kawano Ryuji,
Takinoue Masahiro
Publication year - 2019
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201908392
Subject(s) - nanopore , nanotechnology , amphiphile , materials science , emulsion , dna nanotechnology , dna , chemical engineering , chemistry , polymer , engineering , copolymer , composite material , biochemistry
Bio‐inspired functional microcapsules have attracted increasing attention in many fields from physical/chemical science to artificial‐cell engineering. Although particle‐stabilised microcapsules are advantageous for their stability and functionalisation potential, versatile methods for their functionalisation are desired to expand their possibilities. This study reports a water‐in‐oil microdroplet stabilised with amphiphilic DNA origami nanoplates. By utilising DNA nanotechnology, DNA nanoplates were designed as a nanopore device for ion transportation and to stabilise the oil–water interface. Microscopic examination revealed the microcapsule formed by the accumulation of amphiphilic DNA nanoplates at the oil–water interface. Ion current measurements revealed the nanoplate pores functioned as channel to transport ions. These findings provide a general strategy for the programmable design of microcapsules to engineer artificial cells and molecular robots.