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Inside Back Cover: Nickel‐Catalyzed Asymmetric Hydrogenation of N ‐Sulfonyl Imines (Angew. Chem. Int. Ed. 22/2019)
Author(s) -
Li Bowen,
Chen Jianzhong,
Zhang Zhenfeng,
Gridnev Ilya D.,
Zhang Wanbin
Publication year - 2019
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201905441
Subject(s) - catalysis , nickel , sulfonyl , transition metal , asymmetric hydrogenation , chemistry , hydrogen , combinatorial chemistry , medicinal chemistry , polymer chemistry , enantioselective synthesis , organic chemistry , alkyl
The first nickel‐catalyzed asymmetric hydrogenation of N‐sulfonyl imines using H 2 gas as a hydrogen source has been realized with high catalytic activity (S/C up to 10 500) and excellent enantioselectivity (up to 99.7% ee ). Compared with other transition‐metal catalysts (Rh, Ru, Ir, Pd, etc.), earth‐abundant and inexpensive Ni catalysts are preferable for the preparation of chiral amines on an industrial scale. Details of the study are presented by W. Zhang et al. in their Communication on page 7329.