Premium
Nickel‐Catalyzed Arylboration of Alkenylarenes: Synthesis of Boron‐Substituted Quaternary Carbons and Regiodivergent Reactions
Author(s) -
Chen LiangAn,
Lear Alan R.,
Gao Pin,
Brown M. Kevin
Publication year - 2019
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201904861
Subject(s) - boron , nickel , catalysis , solvent , chemistry , scope (computer science) , quaternary , organic chemistry , combinatorial chemistry , computer science , geology , programming language , paleontology
A method for the construction of boron‐substituted quaternary carbons or diarylquaternary carbons by arylboration of highly substituted alkenylarenes is presented. A wide range of alkenes and arylbromides can participate in this reaction thus allowing for a diverse assortment of products to be prepared. In addition, a solvent dependent regiodivergent arylboration of 1,2‐disubstituted alkenylarenes is presented, thus greatly increasing the scope of products that can be accessed.