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Promoting Frustrated Lewis Pairs for Heterogeneous Chemoselective Hydrogenation via the Tailored Pore Environment within Metal–Organic Frameworks
Author(s) -
Niu Zheng,
Zhang Weijie,
Lan Pui Ching,
Aguila Briana,
Ma Shengqian
Publication year - 2019
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201903763
Subject(s) - frustrated lewis pair , imine , homogeneous , catalysis , amine gas treating , metal organic framework , lewis acids and bases , chemistry , asymmetric hydrogenation , metal , catalytic hydrogenation , combinatorial chemistry , organic chemistry , materials science , enantioselective synthesis , physics , adsorption , thermodynamics
Frustrated Lewis pairs (FLPs) have recently been advanced as efficient metal‐free catalysts for catalytic hydrogenation, but their performance in chemoselective hydrogenation, particularly in heterogeneous systems, has not yet been achieved. Herein, we demonstrate that, via tailoring the pore environment within metal–organic frameworks (MOFs), FLPs not only can be stabilized but also can develop interesting performance in the chemoselective hydrogenation of α,β‐unsaturated organic compounds, which cannot be achieved with FLPs in a homogeneous system. Using hydrogen gas under moderate pressure, the FLP anchored within a MOF that features open metal sites and hydroxy groups on the pore walls can serve as a highly efficient heterogeneous catalyst to selectively reduce the imine bond in α,β‐unsaturated imine substrates to afford unsaturated amine compounds.