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Back Cover: Fuel‐Responsive Allosteric DNA‐Based Aptamers for the Transient Release of ATP and Cocaine (Angew. Chem. Int. Ed. 17/2019)
Author(s) -
Del Grosso Erica,
Ragazzon Giulio,
Prins Leonard J.,
Ricci Francesco
Publication year - 2019
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201903072
Subject(s) - allosteric regulation , aptamer , dissipative system , cover (algebra) , chemistry , biophysics , nanotechnology , materials science , thermodynamics , physics , engineering , receptor , biology , biochemistry , mechanical engineering , genetics
Allosteric DNA‐based nanodevices can transiently load and release small organic molecules (ATP and cocaine). In their Communication on page 5582 ff., F. Ricci, L. J. Prins, and co‐workers demonstrate that allostery, despite being generally considered as a thermodynamic equilibrium phenomenon, offers a key strategy for the rational design of out‐of‐equilibrium synthetic devices. These results provide a new and exciting approach towards the development of functional dissipative systems.