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Catalytic Conjunctive Coupling of Carboxylic Acid Derivatives with 9‐BBN‐Derived Ate Complexes
Author(s) -
Law Chunyin,
Meng Yan,
Koo Seung Moh,
Morken James P.
Publication year - 2019
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201901927
Subject(s) - electrophile , catalysis , carboxylic acid , chemistry , chloride , coupling (piping) , organic chemistry , combinatorial chemistry , medicinal chemistry , materials science , metallurgy
β‐Boryl carbonyl compounds are produced by a Ni‐catalyzed cross‐coupling of vinylboron “ate” complexes and acid chloride or acid anhydride electrophiles. The reactions are efficient, being complete in as little as two minutes, and can be applied to a broad range of substrates.