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Back Cover: Site‐Resolved Observation of Vibrational Energy Transfer Using a Genetically Encoded Ultrafast Heater (Angew. Chem. Int. Ed. 9/2019)
Author(s) -
Baumann Tobias,
Hauf Matthias,
Schildhauer Fabian,
Eberl Katharina B.,
Durkin Patrick M.,
Deniz Erhan,
Löffler Jan G.,
AcevedoRocha Carlos G.,
Jaric Jelena,
Martins Berta M.,
Dobbek Holger,
Bredenbeck Jens,
Budisa Nediljko
Publication year - 2019
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201901297
Subject(s) - energy transfer , femtosecond , ultrashort pulse , cover (algebra) , function (biology) , protein function , vibrational energy , spectroscopy , energy (signal processing) , chemistry , materials science , physics , biology , chemical physics , genetics , gene , molecule , optics , engineering , biochemistry , mechanical engineering , laser , organic chemistry , quantum mechanics
Vibrational energy transfer (VET) in proteins has been linked to allostery and other aspects of protein function in computational studies. In their Communication on page 2899 ff., J. Bredenbeck, N. Budisa, and co‐workers show how vibrational energy can be injected and tracked experimentally in a site‐selective way. By using a genetically encoded ultrafast heater and femtosecond IR spectroscopy, this approach allowed them to map out VET pathways in proteins and to explore the role of VET for protein function.