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Nickel‐Catalyzed Thiolation of Aryl Halides and Heteroaryl Halides through Electrochemistry
Author(s) -
Liu Dong,
Ma HongXing,
Fang Ping,
Mei TianSheng
Publication year - 2019
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201900956
Subject(s) - aryl , halide , catalysis , nickel , electrochemistry , chemistry , transition metal , combinatorial chemistry , sulfur , metal , base (topology) , inorganic chemistry , organic chemistry , electrode , alkyl , mathematical analysis , mathematics
Transition‐metal‐catalyzed coupling reactions are useful tools for synthesizing aryl sulfur compounds. However, conventional transition‐metal‐catalyzed thiolation of aryl bromides and chlorides typically requires the use of strong base under elevated reaction temperature. Herein, we report the first examples of nickel‐catalyzed electrochemical thiolation of aryl bromides and chlorides in the absence of an external base at room temperature using undivided electrochemical cells.