Nickel‐Catalyzed Asymmetric Reductive Diarylation of Vinylarenes

A nickel‐catalyzed asymmetric diarylation reaction of vinylarenes enables the preparation of chiral α,α,β‐triarylated ethane scaffolds, which exist in a number of biologically active molecules. The use of reducing conditions with aryl bromides as coupling partners obviates the need for stoichiometric organometallic reagents and tolerates a broad range of functional groups. The application of an N ‐oxyl radical as a ligand to a nickel catalyst represents a novel approach to facilitate nickel‐catalyzed cross‐coupling reactions.