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Cover Picture: Dual Gold‐Catalyzed Cycloaromatization of Unconjugated ( E )‐Enediynes (Angew. Chem. Int. Ed. 7/2019)
Author(s) -
Zamani Farzad,
Babaahmadi Rasool,
Yates Brian F.,
Gardiner Michael G.,
Ariafard Alireza,
Pyne Stephen G.,
Hyland Christopher J. T.
Publication year - 2019
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201814227
Subject(s) - chemistry , catalysis , moiety , homogeneous , stereochemistry , combinatorial chemistry , organic chemistry , mathematics , combinatorics
Dual gold activation is an important catalytic mode in homogeneous catalysis. In their Communication on page 2114 ff., S. G. Pyne, C. J. T. Hyland, and co‐workers report that ( E )‐enediynes undergo a dual gold‐catalyzed cycloaromatization towards isoindolinones. They use electronic differentiation of triple bonds to direct the formation of a propiolic gold acetylide, represented as a gold‐coveting dragon, which then reacts with a π‐coordinated enyne moiety, illustrated by Rumpelstilzchen spinning his golden thread.