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Inside Back Cover: Enantioselective Electrophilic Aromatic Nitration: A Chiral Auxiliary Approach (Angew. Chem. Int. Ed. 4/2019)
Author(s) -
Campbell Joseph P.,
Rajappan Sinu C.,
Jaynes Tyler J.,
Sharafi Mona,
Ma YongTao,
Li Jianing,
Schneebeli Severin T.
Publication year - 2019
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201814097
Subject(s) - enantioselective synthesis , nitration , electrophile , cover (algebra) , stereoselectivity , chemistry , combinatorial chemistry , stereochemistry , organic chemistry , catalysis , engineering , mechanical engineering
Molecular crane arms deliver nitronium ions to specific locations of concave polyaromatic systems in a stereoselective manner. In their Communication on page 1035 ff., S. T. Schneebeli and co‐workers describe how the first enantioselective aromatic nitration reactions have been achieved with the help of such crane arms. These findings represent a breakthrough in terms of enabling one of the oldest reactions to finally be carried out in an enantioselective manner.