Inside Back Cover: Coiled‐Coil Peptide Beacon: A Tunable Conformational Switch for Protein Detection (Angew. Chem. Int. Ed. 52/2018) | Zendy

Mueller Carolin | Zendy; Grossmann Tom N. | Zendy

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Inside Back Cover: Coiled‐Coil Peptide Beacon: A Tunable Conformational Switch for Protein Detection (Angew. Chem. Int. Ed. 52/2018)

Author(s) -

Mueller Carolin,

Grossmann Tom N.

Publication year - 2018

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Reports

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201813484

Subject(s) - coiled coil , cover (algebra) , peptide , molecular beacon , electromagnetic coil , chemistry , biophysics , physics , biochemistry , biology , engineering , mechanical engineering , oligonucleotide , quantum mechanics , dna

Coiled‐coil peptide beacons consist of a central binding sequence (yellow) and two flanking coiled‐coil‐forming peptides (red). Their hairpin‐like, closed conformation is opened upon receptor (gray) binding. In their Communication on page 17079 ff., C. Mueller and T. N. Grossmann introduce this novel molecular switch and report its use for protein detection.

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