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Back Cover: Paper‐Based Antibody Detection Devices Using Bioluminescent BRET‐Switching Sensor Proteins (Angew. Chem. Int. Ed. 47/2018)
Author(s) -
Tenda Keisuke,
van Gerven Benice,
Arts Remco,
Hiruta Yuki,
Merkx Maarten,
Citterio Daniel
Publication year - 2018
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201811030
Subject(s) - bioluminescence , cover (algebra) , microfluidics , protein detection , antibody , chemistry , nanotechnology , microbiology and biotechnology , materials science , biochemistry , biology , engineering , immunology , mechanical engineering
Detecting antibodies in blood is as simple as it can get. In their Communication on page 15369 ff., D. Citterio, M. Merkx et al. integrate antibody‐targeting bioluminescent sensing proteins and other essential assay components into a microfluidic paper‐based analytical device. A drop of blood, a digital camera, and twenty minutes are all that is required to detect the presence and the concentration of multiple antibodies in whole blood based on the color of the emitted light.