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Incorporation of Homochirality into a Zeolitic Imidazolate Framework Membrane for Efficient Chiral Separation
Author(s) -
Chan Jun Yong,
Zhang Huacheng,
Nolvachai Yada,
Hu Yaoxin,
Zhu Haijin,
Forsyth Maria,
Gu Qinfen,
Hoke David E.,
Zhang Xiwang,
Marriot Philip J.,
Wang Huanting
Publication year - 2018
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201810925
Subject(s) - enantiomer , membrane , zeolitic imidazolate framework , metal organic framework , imidazolate , homochirality , selectivity , chemistry , enantiomeric excess , chiral resolution , enantioselective synthesis , racemic mixture , combinatorial chemistry , organic chemistry , catalysis , adsorption , biochemistry
Homochiral metal–organic frameworks (MOFs) have gained much attention because of their chiral properties and disposition for chiral separation. However, the fabrication of high‐quality homochiral MOF membranes remains challenging because of the difficulty in controlling growth of MOF membranes with chiral functionalities. A homochiral zeolitic imidazolate framework‐8 (ZIF‐8) membrane is reported for efficient chiral separation. The membrane is synthesized by incorporating a natural amino acid, l ‐histidine ( l ‐His), into the framework of ZIF‐8. The homochiral l ‐His‐ZIF‐8 membrane exhibits a good selectivity for the R ‐enantiomer of 1‐phenylethanol over the S ‐enantiomer, showing a high enantiomeric excess value up to 76 %.