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Manganese‐Catalyzed Dual‐Deoxygenative Coupling of Primary Alcohols with 2‐Arylethanols
Author(s) -
Wang Yujie,
Shao Zhihui,
Zhang Kun,
Liu Qiang
Publication year - 2018
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201809333
Subject(s) - catalysis , dehydrogenation , primary (astronomy) , chemistry , deoxygenation , manganese , pincer movement , coupling reaction , coupling (piping) , combinatorial chemistry , dual (grammatical number) , organic chemistry , materials science , physics , art , literature , astronomy , metallurgy
Reported herein is a general and efficient dual‐deoxygenative coupling of primary alcohols with 2‐arylethanols catalyzed by a well‐defined Mn/PNP pincer complex. This reaction is the first example of the catalytic dual‐deoxygenation of alcohols using a non‐noble‐metal catalyst. Both deoxygenative homocoupling of 2‐arylethanols (17 examples) and their deoxygenative cross‐coupling with other primary alcohols (20 examples) proceeded smoothly to form the corresponding alkenes by a dehydrogenation and deformylation reaction sequence.