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Cover Picture: MicroRNA‐Directed Intracellular Self‐Assembly of Chiral Nanorod Dimers (Angew. Chem. Int. Ed. 33/2018)
Author(s) -
Xu Liguang,
Gao Yifan,
Kuang Hua,
LizMarzán Luis M.,
Xu Chuanlai
Publication year - 2018
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201808419
Subject(s) - circular dichroism , nanorod , raman scattering , plasmon , fluorescence , kinetics , materials science , self assembly , nanotechnology , raman spectroscopy , chemistry , crystallography , optoelectronics , optics , physics , quantum mechanics
The chiral self‐assembly of plasmonic nanorod dimers in living cells, driven by complementary binding to a target miRNA sequence, and leading to specific plasmonic circular dichroism, surface‐enhanced Raman scattering (SERS), and fluorescence signals is described in the Communication by H. Kuang, L. M. Liz‐Marzán et al. on page 10544 ff. The method allows in situ imaging as well as highly sensitive and selective miRNA detection. It can also be extended to the study of biomolecular interactions, trafficking, and kinetics inside single living cells.