Borocyclopropanation of Styrenes Mediated by UV‐light Under Continuous Flow Conditions | Zendy

Sayes Morgane | Zendy; Benoit Guillaume | Zendy; Charette André B. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Borocyclopropanation of Styrenes Mediated by UV‐light Under Continuous Flow Conditions

Author(s) -

Sayes Morgane,

Benoit Guillaume,

Charette André B.

Publication year - 2018

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201807347

Subject(s) - styrene , photosensitizer , photochemistry , quenching (fluorescence) , chemistry , continuous flow , xanthone , residence time (fluid dynamics) , combinatorial chemistry , organic chemistry , fluorescence , copolymer , biochemical engineering , polymer , physics , quantum mechanics , engineering , geotechnical engineering

Herein, we report a user‐friendly and metal‐free UV‐A light mediated borocyclopropanation of styrenes using continuous flow technology. A broad range of styrene derivatives can be cyclopropanated in good yields within 1 h residence time to produce highly valuable cyclopropylboronate esters with modest to good diastereoselectivities. The reaction is also applicable to α‐substituted styrenes. Mechanistic studies support a photoredox process during which xanthone, a well‐known organic photosensitizer, can easily reach a photoexcited state that is available for both an oxidative and a reductive quenching.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research