Back Cover: A Regio‐ and Diastereoselective Anodic Aryl–Aryl Coupling in the Biomimetic Total Synthesis of (−)‐Thebaine (Angew. Chem. Int. Ed. 34/2018) | Zendy

Lipp Alexander | Zendy; Ferenc Dorota | Zendy; Gütz Christoph | Zendy; Geffe Mario | Zendy; Vierengel Nina | Zendy; Schollmeyer Dieter | Zendy; Schäfer Hans J. | Zendy; Waldvogel Siegfried R. | Zendy; Opatz Till | Zendy

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Back Cover: A Regio‐ and Diastereoselective Anodic Aryl–Aryl Coupling in the Biomimetic Total Synthesis of (−)‐Thebaine (Angew. Chem. Int. Ed. 34/2018)

Author(s) -

Lipp Alexander,

Ferenc Dorota,

Gütz Christoph,

Geffe Mario,

Vierengel Nina,

Schollmeyer Dieter,

Schäfer Hans J.,

Waldvogel Siegfried R.,

Opatz Till

Publication year - 2018

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201806821

Subject(s) - thebaine , aryl , substrate (aquarium) , cover (algebra) , chemistry , coupling (piping) , stereochemistry , combinatorial chemistry , materials science , organic chemistry , engineering , alkyl , oceanography , codeine , morphine , pharmacology , geology , mechanical engineering , metallurgy , medicine

Enforcement of selectivity through a combination of electrochemistry and substrate design enabled the biomimetic synthesis of the economically important opium alkaloid (−)‐thebaine. In their Communication on page 11055 ff., T. Opatz and co‐workers present a regio‐ and diastereoselective anodic coupling of 3′,4′,5′‐trioxygenated laudanosine derivatives, thereby helping to overcome a long‐standing electrosynthetic challenge. Graphic edited by L. Großmann (Mainz).

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