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Cover Picture: Exposing the Origins of Irreproducibility in Fluorine NMR Spectroscopy (Angew. Chem. Int. Ed. 30/2018)
Author(s) -
Rosenau Carl Philipp,
Jelier Benson J.,
Gossert Alvar D.,
Togni Antonio
Publication year - 2018
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201805557
Subject(s) - fluorine 19 nmr , nuclear magnetic resonance spectroscopy , trace (psycholinguistics) , chemistry , chemical nomenclature , nmr spectra database , guideline , analytical chemistry (journal) , organic chemistry , spectral line , political science , philosophy , physics , linguistics , astronomy , law
One possible barrier to scientific reproducibility is the lack of clear protocols. This is the case for the 19 F NMR referencing of fluorine‐containing compounds. In their Communication on page 9528 ff., A. D. Gossert, A. Togni, and co‐workers trace back the origins of this problem to poor definitions for 19 F NMR spectroscopy in IUPAC′s unified scale and systematic errors by instrument manufacturers. These difficulties are easily overcome by following a simple procedure, which will serve the community as a modern guideline for the referencing of 19 F NMR spectra.