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Cover Picture: Transport of Nucleoside Triphosphates into Cells by Artificial Molecular Transporters (Angew. Chem. Int. Ed. 31/2018)
Author(s) -
Zawada Zbigniew,
Tatar Ameneh,
Mocilac Pavle,
Buděšínský Miloš,
Kraus Tomáš
Publication year - 2018
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201805221
Subject(s) - nucleoside , nucleoside transporter , biochemistry , intracellular , chemistry , transporter , membrane transport , nucleotide , facilitated diffusion , dna , membrane , biophysics , biology , gene
Transport of nucleoside triphosphates across cell membranes does not proceed under ambient conditions. In their Communication on page 9891 ff., T. Kraus et al. show rapid and selective transport of various fluorescently labeled nucleoside triphosphates (NTPs) into eukaryotic and prokaryotic cells by artificial transporters. The labeled NTPs, which are instantly released in the intracellular space, can be exploited for tracing metabolic processes such as DNA synthesis in live cells.