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Inside Cover: A Dynamic Chemical Network for Cystinuria Diagnosis (Angew. Chem. Int. Ed. 28/2018)
Author(s) -
Lafuente Maria,
Solà Jordi,
Alfonso Ignacio
Publication year - 2018
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201804532
Subject(s) - cystinuria , cystine , cover (algebra) , signal (programming language) , cysteine , computer science , chemistry , biochemistry , engineering , mechanical engineering , programming language , enzyme
Sensing cysteine and cystine is possible with a dynamic system in which rearrangement of the components leads to a readable signal. In their Communication on page 8421 ff. M. Lafuente, J. Solà, and I. Alfonso show that this conceptually new approach works in aqueous media and in human urine, thus making it a potential diagnostic tool for cystinuria. The picture highlights the self‐association of the dynamic‐sensor‐like pieces of a puzzle that produces a fluorescent entity, represented by a light bulb. Picture credits @ChemBioUSC.