Premium
Inside Cover: Polyvalent Display of Biomolecules on Live Cells (Angew. Chem. Int. Ed. 23/2018)
Author(s) -
Shi Peng,
Zhao Nan,
Lai Jinping,
Coyne James,
Gaddes Erin R.,
Wang Yong
Publication year - 2018
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201803945
Subject(s) - biomolecule , cover (algebra) , supramolecular chemistry , nanotechnology , chemistry , materials science , molecule , engineering , mechanical engineering , organic chemistry
Supramolecular engineering of cell surfaces was explored as a means to display polyvalent biomolecules on live cells using branched DNA polymers. In their Communication on page 6800 ff., Y. Wang et al. show that by using polyvalent surface display of biomolecules, the ability of engineered cells to recognize the microenvironment can be enhanced by at least an order of magnitude.