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Electrooxidative Rhodium‐Catalyzed C−H/C−H Activation: Electricity as Oxidant for Cross‐Dehydrogenative Alkenylation
Author(s) -
Qiu Youai,
Kong WeiJun,
Struwe Julia,
Sauermann Nicolas,
Rogge Torben,
Scheremetjew Alexej,
Ackermann Lutz
Publication year - 2018
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201803342
Subject(s) - rhodium , chemistry , catalysis , electrochemistry , oxidative phosphorylation , stoichiometry , platinum , combinatorial chemistry , metal , organic chemistry , biochemistry , electrode
Rhodium(III) catalysis has enabled a plethora of oxidative C−H functionalizations, which predominantly employ stoichiometric amounts of toxic and/or expensive metal oxidants. In contrast, we herein describe the first electrochemical rhodium‐catalyzed C−H activation that avoids hazardous chemical oxidants. Environmentally benign twofold C−H/C−H functionalizations were accomplished with weakly coordinating benzoic acids and benzamides, employing electricity as the terminal oxidant and generating H 2 as the sole byproduct.