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MaxSynBio: Avenues Towards Creating Cells from the Bottom Up
Author(s) -
Schwille Petra,
Spatz Joachim,
Landfester Katharina,
Bodenschatz Eberhard,
Herminghaus Stephan,
Sourjik Victor,
Erb Tobias J.,
Bastiaens Philippe,
Lipowsky Reinhard,
Hyman Anthony,
Dabrock Peter,
Baret JeanChristophe,
VidakovicKoch Tanja,
Bieling Peter,
Dimova Rumiana,
Mutschler Hannes,
Robinson Tom,
Tang T.Y. Dora,
Wegner Seraphine,
Sundmacher Kai
Publication year - 2018
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201802288
Subject(s) - synthetic biology , construct (python library) , modular design , living systems , top down and bottom up design , basic research , computer science , engineering , biology , computational biology , ecology , software engineering , programming language , operating system , library science
A large German research consortium mainly within the Max Planck Society (“MaxSynBio”) was formed to investigate living systems from a fundamental perspective. The research program of MaxSynBio relies solely on the bottom‐up approach to synthetic biology. MaxSynBio focuses on the detailed analysis and understanding of essential processes of life through modular reconstitution in minimal synthetic systems. The ultimate goal is to construct a basic living unit entirely from non‐living components. The fundamental insights gained from the activities in MaxSynBio could eventually be utilized for establishing a new generation of biotechnological processes, which would be based on synthetic cell constructs that replace the natural cells currently used in conventional biotechnology.