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Photocatalyzed ortho ‐Alkylation of Pyridine N ‐Oxides through Alkene Cleavage
Author(s) -
Zhou Wang,
Miura Tomoya,
Murakami Masahiro
Publication year - 2018
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201801305
Subject(s) - alkene , pyridine , alkylation , chemistry , cleavage (geology) , medicinal chemistry , alkyl , bond cleavage , organic chemistry , catalysis , materials science , fracture (geology) , composite material
A photocatalyzed reaction of pyridine N ‐oxides with alkenes gives ortho ‐alkylated pyridines with cleavage of the carbon–carbon double bond. Benzyl and secondary alkyl groups are incorporated at the ortho position of pyridines in one pot.