Unprecedented Dearomatized Spirocyclopropane in a Sequential Rhodium(III)‐Catalyzed C−H Activation and Rearrangement Reaction | Zendy

Wang Xiaoming | Zendy; Li Yingzi | Zendy; Knecht Tobias | Zendy; Daniliuc Constantin G. | Zendy; Houk K. N. | Zendy; Glorius Frank | Zendy

Premium

Unprecedented Dearomatized Spirocyclopropane in a Sequential Rhodium(III)‐Catalyzed C−H Activation and Rearrangement Reaction

Author(s) -

Wang Xiaoming,

Li Yingzi,

Knecht Tobias,

Daniliuc Constantin G.,

Houk K. N.,

Glorius Frank

Publication year - 2018

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201800803

Subject(s) - rhodium , catalysis , chemistry , medicinal chemistry , organic chemistry

An unprecedented dearomatized spirocyclopropane intermediate was discovered in a sequential Cp*Rh III ‐catalyzed C−H activation and Wagner–Meerwein‐type rearrangement reaction. How the oxidative O−N bond is cleaved and the role of HOAc were uncovered in this study. Furthermore, a Cp*Rh III ‐catalyzed dearomatization reaction of N ‐(naphthalen‐1‐yloxy)acetamide with strained olefins was developed, affording a variety of spirocyclopropanes.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research