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A [3]Rotaxane Host Selects Between Stereoisomers
Author(s) -
Denis Mathieu,
Goldup Stephen Michael
Publication year - 2018
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201800665
Subject(s) - rotaxane , stereoselectivity , stereochemistry , host (biology) , chemistry , binding site , biology , molecule , genetics , biochemistry , organic chemistry , supramolecular chemistry , catalysis
What has it got in its pockets? A new approach to the selective binding and reporting of stereoisomers using mechanical bonding to produce a well‐defined three‐dimensional binding pocket was recently reported by Beer and co‐workers. The highly stereoselective binding of stereoisomers by the reported [3]rotaxane suggest that the use of the mechanical bond to engineer a binding pocket has great potential for the development of stereoselective hosts.