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Synergistic Photoredox Catalysis and Organocatalysis for Inverse Hydroboration of Imines
Author(s) -
Zhou Nengneng,
Yuan XiangAi,
Zhao Yue,
Xie Jin,
Zhu Chengjian
Publication year - 2018
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201800421
Subject(s) - hydroboration , organocatalysis , chemistry , boranes , carbene , catalysis , combinatorial chemistry , photoredox catalysis , photocatalysis , organic chemistry , enantioselective synthesis , boron
The first catalytic inverse hydroboration of imines with N‐heterocyclic carbene (NHC) boranes has been realized by means of cooperative organocatalysis and photocatalysis. This catalytic combination provides a promising platform for promoting NHC‐boryl radical chemistry under sustainable and radical‐initiator‐free conditions. The highly important functional‐group compatibility and possible application in late‐stage hydroborations represent an important step forward to an enhanced α‐amino organoboron library.