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Electrochemical Oxidative C−H Amination of Phenols: Access to Triarylamine Derivatives
Author(s) -
Tang Shan,
Wang Siyuan,
Liu Yichang,
Cong Hengjiang,
Lei Aiwen
Publication year - 2018
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201800240
Subject(s) - amination , oxidative phosphorylation , electrochemistry , phenols , chemistry , combinatorial chemistry , organic chemistry , catalysis , biochemistry , electrode
Dehydrogenative C−H/N−H cross‐coupling serves as one of the most straightforward and atom‐economical approaches for C−N bond formation. In this work, an electrochemical reaction protocol has been developed for the oxidative C−H amination of unprotected phenols under undivided electrolytic conditions. Neither metal catalysts nor chemical oxidants are needed to facilitate the dehydrogenation process. A series of triarylamine derivatives could be obtained with good functional‐group tolerance. The electrolysis is scalable and can be performed at ambient conditions.