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Palladium‐Catalyzed Atom‐Transfer Radical Cyclization at Remote Unactivated C(sp 3 )−H Sites: Hydrogen‐Atom Transfer of Hybrid Vinyl Palladium Radical Intermediates
Author(s) -
Ratushnyy Maxim,
Parasram Marvin,
Wang Yang,
Gevorgyan Vladimir
Publication year - 2018
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201712775
Subject(s) - palladium , hydrogen atom , chemistry , catalysis , photochemistry , radical cyclization , atom transfer radical polymerization , atom (system on chip) , hydrogen , medicinal chemistry , organic chemistry , group (periodic table) , polymerization , polymer , computer science , embedded system
A novel mild, visible‐light‐induced palladium‐catalyzed hydrogen atom translocation/atom‐transfer radical cyclization (HAT/ATRC) cascade has been developed. This protocol involves a 1,5‐HAT process of previously unknown hybrid vinyl palladium radical intermediates, thus leading to iodomethyl carbo‐ and heterocyclic structures.

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