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Engineering Proteins at Interfaces: From Complementary Characterization to Material Surfaces with Designed Functions
Author(s) -
Morsbach Svenja,
Gonella Grazia,
Mailänder Volker,
Wegner Seraphine,
Wu Si,
Weidner Tobias,
Berger Rüdiger,
Koynov Kaloian,
Vollmer Doris,
Encinas Noemí,
Kuan Seah Ling,
Bereau Tristan,
Kremer Kurt,
Weil Tanja,
Bonn Mischa,
Butt HansJürgen,
Landfester Katharina
Publication year - 2018
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201712448
Subject(s) - characterization (materials science) , nanotechnology , adsorption , surface (topology) , protein adsorption , materials science , computer science , biochemical engineering , engineering , chemistry , mathematics , geometry , organic chemistry
Once materials come into contact with a biological fluid containing proteins, proteins are generally—whether desired or not—attracted by the material's surface and adsorb onto it. The aim of this Review is to give an overview of the most commonly used characterization methods employed to gain a better understanding of the adsorption processes on either planar or curved surfaces. We continue to illustrate the benefit of combining different methods to different surface geometries of the material. The thus obtained insight ideally paves the way for engineering functional materials that interact with proteins in a predetermined manner.

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