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Peripheral Templation‐Modulated Interconversion between an A 4 L 6 Tetrahedral Anion Cage and A 2 L 3 Triple Helicate with Guest Capture/Release
Author(s) -
Bai Xuemin,
Jia Chuandong,
Zhao Yanxia,
Yang Dong,
Wang ShiCheng,
Li Anyang,
Chan YiTsu,
Wang YaoYu,
Yang XiaoJuan,
Wu Biao
Publication year - 2018
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201712080
Subject(s) - chemistry , cage , ligand (biochemistry) , tetrahedron , crystallography , ion , urea , stereochemistry , receptor , organic chemistry , biochemistry , mathematics , combinatorics
An anion‐coordination‐based A 4 L 6 (“A” denotes anion and “L” is ligand) tetrahedral cage was constructed by a C 2 ‐symmetric bis‐bis(urea) ligand and phosphate anion, which showed reversible interconversion with the A 2 L 3 triple helicate as a response to the template, concentration, or solvent. Notably, an unusual “peripheral” templation was found to be critical to stabilize the tetrahedral structure. This peripheral effect was utilized to assemble an “empty” A 4 L 6 cage that allows the multi‐stimuli‐controlled capture/release of biologically important species such as choline and acetylcholine.