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Efficient Synthesis of Arylated Furans by a Sequential Rh‐Catalyzed Arylation and Cycloisomerization of Cyclopropenes
Author(s) -
Wang Xiaoming,
Lerchen Andreas,
Daniliuc Constantin G.,
Glorius Frank
Publication year - 2018
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201712019
Subject(s) - cycloisomerization , chemistry , catalysis , combinatorial chemistry , organic chemistry
A novel and efficient strategy for the synthesis of arylated furans was successfully developed by a Rh III ‐catalyzed coupling of N ‐phenoxyacetamides and cyclopropenyl esters. Mechanistic investigation reveals that the arylated furans are formed via arylation of the cyclopropenyl esters followed by cycloisomerization.