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Cobalt‐Catalyzed Suzuki Biaryl Coupling of Aryl Halides
Author(s) -
Asghar Soneela,
Tailor Sanita B.,
Elorriaga David,
Bedford Robin B.
Publication year - 2017
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201710053
Subject(s) - cobalt , aryl , catalysis , chemistry , halide , suzuki reaction , carbene , combinatorial chemistry , palladium , organic chemistry , alkyl
Readily accessed cobalt pre‐catalysts with N‐heterocyclic carbene ligands catalyze the Suzuki cross‐coupling of aryl chlorides and bromides with alkyllithium‐activated arylboronic pinacolate esters. Preliminary mechanistic studies indicate that the cobalt species is reduced to Co 0 during the reaction.