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Efficient Water Reduction with sp 3 ‐sp 3 Diboron(4) Compounds: Application to Hydrogenations, H–D Exchange Reactions, and Carbonyl Reductions
Author(s) -
Flinker Mathias,
Yin Hongfei,
Juhl René W.,
Eikeland Espen Z.,
Overgaard Jacob,
Nielsen Dennis U.,
Skrydstrup Troels
Publication year - 2017
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201709685
Subject(s) - chemistry , reduction (mathematics) , medicinal chemistry , radiochemistry , inorganic chemistry , mathematics , geometry
A series of crystalline sp 3 ‐sp 3 diboron(4) compounds were synthesized and shown to promote the facile reduction of water with dihydrogen formation. The application of these diborons as simple and effective dihydrogen and dideuterium sources was demonstrated by conducting a series of selective reductions of alkynes and alkenes, and hydrogen–deuterium exchange reactions using two‐chamber reactors. Finally, as the water reduction reaction generates an intermediate borohydride species, a range of aldehydes and ketones were reduced by using water as the hydride source.