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Cover Picture: Cytoprotective Encapsulation of Individual Jurkat T Cells within Durable TiO 2 Shells for T‐Cell Therapy (Angew. Chem. Int. Ed. 36/2017)
Author(s) -
Youn Wongu,
Ko Eun Hyea,
Kim MiHee,
Park Matthew,
Hong Daewha,
Seisenbaeva Gulaim A.,
Kessler Vadim G.,
Choi Insung S.
Publication year - 2017
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201706513
Subject(s) - jurkat cells , nanomedicine , nanotechnology , chemistry , ctl* , in vitro , t cell , materials science , biophysics , immune system , microbiology and biotechnology , immunology , nanoparticle , cytotoxic t cell , medicine , biology , biochemistry
Cell‐in‐shell structures, also known as artificial spores, have great potential in nanomedicine because of their enhanced viability during in vitro manipulation and storage. In their Communication on page 10702 ff., I. S. Choi, V. Kessler, D. Hong, et al. report that Jurkat T cells maintain their therapeutically relevant activities, including antigen–antibody interactions and interleukin‐2 secretion, while acquiring enhanced tolerance against harmful stressors, after durable TiO 2 shell formation.